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Another new CRISPR tool was just published by MIT researchers.
PASTE allows for the editing of large swaths of DNA without having to create double strand breaks needing to then go through the DNA repair process
Highly accurate and efficient, this could drastically improve CRISPR gene editing options.
#CRISPR #Biotech #Biotechnology #GMO #GeneEditing #DSB #MIT #sciencemastodon #academicmastodon #scicomm
NatureDrag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases - Nature BiotechnologyLarge sequences are integrated site specifically into the human genome without double-strand DNA cleavage.