Centuries ago, I published a manuscript on BioRχiv about the love/hate relationship between variability and robustness in embryogenesis.
And now, it's published in Science! I am so proud
https://www.science.org/doi/10.1126/science.adh1145
We went through three (3!) rounds of revisions. Although we did not change a comma in the abstract, the revisions improved the quality of the work very much (we nearly doubled the sample size and added an entire figure).