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Journal of Cell Science

From our current cover:
Dunn &co show that the coiled-coil protein mutated in colorectal cancer (MCC) localises to the centrosome in proliferating cells in intestinal crypts, and upon terminal differentiation, redeploys to non-centrosomal apical sites, mediated by phosphorylation of MCC by casein kinase 1δ and ε.
journals.biologists.com/jcs/ar

The image shows a panoramic cross-section view of a mouse small intestinal villus, revealing MCC protein (red) distribution at the apical membrane, with β-catenin (green) outlining the lateral cell membrane. Nuclei are in blue.
Nov 29, 2022, 10:47 AM·Public·Web
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