Three #SARS-CoV-2 #spike protein #variants delivered intranasally by #measles and #mumps #vaccines are broadly protective https://www.nature.com/articles/s41467-024-49443-2
In this study, the authors developed intranasal measles virus and mumps virus-based trivalent vaccines, each expressing three distinct SARS-CoV-2 stabilized prefusion spike proteins. They show that the intranasal vaccines provide protection against infection of SARS-CoV-2 variants in small animal models.
NatureThree SARS-CoV-2 spike protein variants delivered intranasally by measles and mumps vaccines are broadly protective - Nature CommunicationsIn this study, the authors developed intranasal measles virus and mumps virus-based trivalent vaccines, each expressing three distinct SARS-CoV-2 stabilized prefusion spike proteins. They show that the intranasal vaccines provide protection against infection of SARS-CoV-2 variants in small animal models.