#Antigenicity and #infectivity characterisation of #SARS-CoV-2 #BA286, Lancet Infect Dis.: https://doi.org/10.1016/S1473-3099(23)00573-X #research #science #covid19
''In summary... #BA286 is antigenically distinct from #XBB15 & previous #Omicron variants, & can evade XBB-induced & XBB-effective neutralising Abs targeting various epitopes... efficacy of developing XBB-based #vaccines vs BA.2.86 should be closely monitored & carefully evaluated... BA.2.86 has a lower efficiency in infecting cell lines in vitro. However, BA.2.86 might obtain additional mutations during its transmission to enhance its infectivity...''
@GMIK69 Marc Johnson (SolidEvidence at TwitChan) mentioned an S:456L mutation, suggested this was particularly nasty. Is this related? Just curious, I'm not a phylogeneticist but i still try to keep up sometimes
@RebelGeek99 In the context of multiple VOI/VUM circulation, where the EG.5.x lineage viruses seem to predominate so far in currents epidemics, the BA286 fate remains to be determined in the next few weeks, with the incoming of respiratory viruses season.