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#Fibroblast-expressed LRRC15 is a #receptor for #SARS-CoV-2 #spike and controls #antiviral and #antifibrotic transcriptional programs https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001967
journals.plos.orgFibroblast-expressed LRRC15 is a receptor for SARS-CoV-2 spike and controls antiviral and antifibrotic transcriptional programsMolecular interactions between SARS-CoV-2 and its host dictate the course of COVID-19 disease progression; this study identifies LRRC15 as a new fibroblast SARS-CoV-2 spike receptor that can block infection, activate cellular antiviral programs, and suppress collagen production.