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CellBioNews<p><a href="https://scientificnetwork.de/tags/Bacteria" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Bacteria</span></a> <a href="https://scientificnetwork.de/tags/evolved" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>evolved</span></a> to help neighboring <a href="https://scientificnetwork.de/tags/cells" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>cells</span></a> after death, new research reveals.</p><p><a href="https://scientificnetwork.de/tags/nutrients" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>nutrients</span></a> <a href="https://scientificnetwork.de/tags/clonal_colonies" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>clonal_colonies</span></a> <a href="https://scientificnetwork.de/tags/protein" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>protein</span></a> <a href="https://scientificnetwork.de/tags/catabolism" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>catabolism</span></a> <a href="https://scientificnetwork.de/tags/bacterio_altruism" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>bacterio_altruism</span></a> <a href="https://scientificnetwork.de/tags/Ecoli" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>Ecoli</span></a> <a href="https://scientificnetwork.de/tags/senescence" class="mention hashtag" rel="nofollow noopener noreferrer" target="_blank">#<span>senescence</span></a> </p><p> <a href="https://phys.org/news/2025-02-bacteria-evolved-neighboring-cells-death.html" rel="nofollow noopener noreferrer" translate="no" target="_blank"><span class="invisible">https://</span><span class="ellipsis">phys.org/news/2025-02-bacteria</span><span class="invisible">-evolved-neighboring-cells-death.html</span></a></p>
Microjo<p>It&#39;s official, the final version of our newest research is out in The ISME Journal: &quot;Bacteria use a catabolic patchwork pathway of apparently recent origin for degradation of the synthetic buffer compound TRIS&quot;</p><p>Read all about how <a href="https://mstdn.science/tags/Pseudomonas" class="mention hashtag" rel="tag">#<span>Pseudomonas</span></a> and other <a href="https://mstdn.science/tags/bacteria" class="mention hashtag" rel="tag">#<span>bacteria</span></a> have learned to eat our well-beloved <a href="https://mstdn.science/tags/TRIS" class="mention hashtag" rel="tag">#<span>TRIS</span></a> buffer. </p><p><a href="https://doi.org/10.1093/ismejo/wrad023" target="_blank" rel="nofollow noopener noreferrer" translate="no"><span class="invisible">https://</span><span class="">doi.org/10.1093/ismejo/wrad023</span><span class="invisible"></span></a> </p><p><a href="https://mstdn.science/tags/microbiology" class="mention hashtag" rel="tag">#<span>microbiology</span></a> <a href="https://mstdn.science/tags/catabolism" class="mention hashtag" rel="tag">#<span>catabolism</span></a> <a href="https://mstdn.science/tags/ISME" class="mention hashtag" rel="tag">#<span>ISME</span></a> <a href="https://mstdn.science/tags/HGT" class="mention hashtag" rel="tag">#<span>HGT</span></a> <a href="https://mstdn.science/tags/plasmid" class="mention hashtag" rel="tag">#<span>plasmid</span></a> <a href="https://mstdn.science/tags/OA" class="mention hashtag" rel="tag">#<span>OA</span></a> <a href="https://mstdn.science/tags/evolution" class="mention hashtag" rel="tag">#<span>evolution</span></a></p>
Joseph P.<p>However, high doses of ATP can lead to an increase in matrix <a href="https://mstdn.science/tags/metalloproteinase" class="mention hashtag" rel="tag">#<span>metalloproteinase</span></a> 13 (MMP-13) activity and extracellular inorganic pyrophosphate (ePPi) accumulation, which can lead to undesirable effects such as <a href="https://mstdn.science/tags/mineralization" class="mention hashtag" rel="tag">#<span>mineralization</span></a> of articular cartilage. Therefore, the purpose of this study is to identify the mechanism of ATP-mediated <a href="https://mstdn.science/tags/catabolism" class="mention hashtag" rel="tag">#<span>catabolism</span></a> and to determine a therapeutic dose range to maximize the <a href="https://mstdn.science/tags/anabolic" class="mention hashtag" rel="tag">#<span>anabolic</span></a> effect.</p>