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Recently, I had conversations with 2 people who turned out to be vaccine skeptics. They stopped getting #COVID vaccines after their first jab or two. So, I told them about the 30+ year history behind mRNA vaccine development. That it has been (and continues to be) worked on for treating cancer as well as for other diseases. And that mRNA vaccines were part-way developed for #SARS during the 2002-2004 outbreak (but work stopped because the infection petered out for various reasons) and for Zika. And that when the pandemic came along, most of the pieces of for creating an #mRNA #vaccine for COVID were already in place -- which is why the the vaccines came out relatively quickly. And that they underwent clinical trials before they were approved for release.
Both conversations ended with "Wow, I didn't know any of that. You've given me something to think about."
I'll take it as a win.
Sometimes it's #history more than #science that can help get a message across.

Sources:
1.Timeline: niaid.nih.gov/diseases-conditi
2. One of the best summaries of the mRNA vaccine and its history. statnews.com/2020/11/10/the-st

#publichealth @medmastodon #medmastodon #IDmastodon

Novo:

Malária Fone: 24h a serviço da população

No dia Mundial de Luta Contra a Malária, o 'Malária Fone', linha que esclarece dúvidas e fornece orientações sobre a doença, celebrou a marca de mais de 600 atendimentos realizados apenas em 2015
Por Lucas Rocha

24/04/2015 - Atualizado em 02/09/2024

ioc.fiocruz.br/noticias/malari

#Malaria
#IDMastodon
#Brasil

#Sars-CoV-2 (#COVID) found in samples of multiple species of #wildlife in the US. From a short news report in JAMA regarding a study in Nature Comm.
"SARS-CoV-2, the #virus that causes COVID-19, has previously been identified in certain species of wildlife, including white-tailed deer. But new research in Nature Communications suggests it may be common in other types of wildlife, especially species living near high-trafficked human areas.
The researchers took nasal and oral swabs from 23 common wildlife species in Virginia and Washington, DC, between May 2022 and September 2023. They detected the virus in 6 species of deer mouse, opossum, raccoon, groundhog, rabbit, and bat. The researchers also collected 126 blood samples from these 6 species, with 5 species displaying antibodies that indicated prior exposure. Their analysis showed that antibody detection was 3 times higher in animals near hiking trails and high-traffic public areas than in low human-use areas.

Additionally, the virus isolated from an opossum in 2022 showed previously unreported mutations, suggesting animal-to-animal transmission, the researchers reported. Although there is no evidence of viral transmission from animals to humans, the researchers stressed the need for further surveillance of novel mutations that could endanger wildlife and humans."
#Medmastodon @Medmastodon #IDmastodon #infectiousdiseases
The Nature study: nature.com/articles/s41467-024

NatureWidespread exposure to SARS-CoV-2 in wildlife communities - Nature CommunicationsThe wildlife host range of SARS-CoV-2 is currently unknown. Here, the authors report evidence of infection in six common wild animal species (deer mouse, Virginia opossum, raccoon, groundhog, Eastern cottontail, Eastern red bat) out of 23 species tested in Virginia and Washington DC, USA in 2022/2023.