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Joseph P.

Treatments such as PD-1/PD-L1 blockade and @chemokine modulation have been successful in modifying the interactions between the immune system and cancer, leading to the rejection or suppression of progression. Cancer cells can also alter the immune microenvironment, leading to and evasion. In this research paper, the authors studied the microenvironment in metastases and identified a network of cells and immune cells that exploit the CCL5-CCR5 axis.