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Joseph P.

However, high doses of ATP can lead to an increase in matrix 13 (MMP-13) activity and extracellular inorganic pyrophosphate (ePPi) accumulation, which can lead to undesirable effects such as of articular cartilage. Therefore, the purpose of this study is to identify the mechanism of ATP-mediated and to determine a therapeutic dose range to maximize the effect.

Dec 06, 2022, 09:11 AM·Public·Web
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