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Sterling Ericsson

As with organ transplants, stem cells trigger an immune response when used in medical treatments, potentially leading to rejection of the cells.

To prevent this, Sana Biotechnology scientists have developed stem cells with removed HLA markers that survived uninhibited in rhesus macaques for months.

This opens up whole new prospects for medical treatment of organs and tissues.

nature.com/articles/s41587-023

NatureHypoimmune induced pluripotent stem cells survive long term in fully immunocompetent, allogeneic rhesus macaques - Nature BiotechnologyA genetic method to block immune rejection of allogeneic cells is validated in monkeys.