Just in case anyone in #TeamMassSpec is curious, the likely culprit of my 248.9 m/z ion from this thread: https://mstdn.science/@sarahehancock/110818463525422168 is free cyanide reacting with the gold seals of the HPLC pump. I will have to try a few different brands of solvent to see if I can ameliorate this issue. More info also available here: https://community.agilent.com/technical/lcms/f/forum/5480/how-do-we-get-rid-of-identify-contamination-with-m-z-248-9737-negative-mode.