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#macrophages are an integral part of the solid tumor #microenvironment and have complex roles in #Immunology , #inflammation and #tissue homeostasis. Here is an elegant review on the topic of #innateimmunity in #cancer
https://www.cell.com/cell/fulltext/S0092-8674(23)00163-0
CellMacrophages at the interface of the co-evolving cancer ecosystemTumor-associated macrophages (TAMs) fuel the evolution of the cancer ecosystem. This
review discusses recent advances in our knowledge of macrophages in the tumor microenvironment,
broadly covering TAM functions, factors that shape macrophage heterogeneity, macrophage
and tumor co-evolution, and therapeutic opportunities.