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RT @RischZack
@TumorBoardTues @MPishvaian @JohnEbbenMDPhD @CCAlliance @shafiarahman_ @ASCO 4/22 #TumorBoardTuesday
Mini tweetorial 2

RAS Mutation = resistance to anti-EGFR therapy

KRAS muts: detected by NGS- tissue or liquid bx #ctDNA

≈49% of #CRC= KRAS/NRAS muts
KRAS codons 12 (30%) & 13 (~8%) of exon 2. NRAS (exons 2, 3, 4)
https://pubmed.ncbi.nlm.nih.gov/26189770/