#Hemagglutinin and #neuraminidase of a non-pathogenic #H7N7 avian #influenza virus coevolved during acquisition of intranasal #pathogenicity in #chickens, Arch Virol.: https://link.springer.com/article/10.1007/s00705-024-06118-z
This study demonstrates that viruses that are highly pathogenic when administered intranasally require additional adaptations for increased pathogenicity to be highly lethal to intranasally infected chickens.