''Cranial #nerves, especially the #olfactory nerve, are important routes of #neuroinvasion for HPAI H5Nx viruses.
HPAI H5Nx viruses have a broad neurotropic potential and can efficiently infect and replicate in various #CNS cell types.
Vaccination and/or antiviral therapy might in part prevent neuroinvasion and neurological disease following HPAI H5Nx virus infection, although comprehensive studies in this area are lacking.''