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Elevated #binding and functional #antibody responses to #SARS-CoV-2 in #infants versus #mothers, Nat Commun.: https://www.nature.com/articles/s41467-023-40554-w #immunity #immunology #pregnancy #pediatrics #medicine #research
NatureElevated binding and functional antibody responses to SARS-CoV-2 in infants versus mothers - Nature CommunicationsData on antibody response to SARS-CoV-2 in infants directly compared with their mothers is limited. Stoddard et al. find distinct antibody profiles in infants, including elevated levels of antibody binding to Spike, elevated ADCC, and convergent antibody binding escape profiles in the Spike fusion peptide.
''These #results suggest #infants develop distinct SARS-CoV-2 binding and functional antibody activities and reveal age-related differences in humoral #immunity to SARS-CoV-2 #infection that could be relevant to protection and #COVID19 disease outcomes.''